2. Gene
  3. Prdx1 - peroxiredoxin 1 Gene

Prdx1 - peroxiredoxin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hbp23

Gene ID: 117254 | Gene type: protein coding

About Prdx1

Summary

Enables heme binding activity; identical protein binding activity; and peroxiredoxin activity. Involved in response to oxidative stress. Located in several cellular components, including euchromatin; mitochondrial matrix; and peroxisomal matrix. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Orthologous to human PRDX1 (peroxiredoxin 1). [provided by Alliance of Genome Resources, Apr 2022]

Prdx1 Products(1)

mRNA Protein Name
NM_057114.3 NP_476455.1 peroxiredoxin-1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables heme binding IPI
IPI: Inferred from physical interaction
7577926 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
10535922 RGD
enables peroxiredoxin activity IDA
IDA: Inferred from direct assay
7488219 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
17556052 RGD
Cellular Component GO Annotation Evidence Reference Source
located in euchromatin IDA
IDA: Inferred from direct assay
14623930 RGD
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
14623930 RGD
located in peroxisomal matrix IDA
IDA: Inferred from direct assay
14623930 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxiredoxin-1

heme-binding 23 kDa protein

thioredoxin peroxidase 2

thioredoxin-dependent peroxide reductase 2

thioredoxin-dependent peroxiredoxin 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-149394 PRDX1-IN-1 98.04% Unkown
HY-122936 Tanshindiol C 98.47% Unkown
HY-133541 Glucopiericidin A / Unkown
HY-158368 PRDX1-IN-2 Inhibitor / Unkown
HY-171272 PRDX1-IN-3 / Unkown
HY-RS11074 PRDX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16694 Prdx1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23129 Prdx1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdx1 NCBI NCBI:5052
Mus musculus Prdx1 NCBI NCBI:18477