2. Gene
  3. HMGA1 - Hmga1 high mobility group AT-hook 1 Gene

HMGA1 - Hmga1 high mobility group AT-hook 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hmgi; Hmgiy

Gene ID: 117062 | Gene type: protein coding

About HMGA1

Summary

Predicted to enable several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and catalytic activity, acting on DNA. Predicted to be involved in several processes, including oncogene-induced cell senescence; positive regulation of cellular senescence; and regulation of transcription, DNA-templated. Predicted to act upstream of or within spermatogenesis. Predicted to be located in senescence-associated heterochromatin focus. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human HMGA1 (high mobility group AT-hook 1). [provided by Alliance of Genome Resources, Apr 2022]

HMGA1 Products(2)

mRNA Protein Name
NM_001412159.1 NP_001399088.1 high mobility group protein HMG-I/HMG-Y
NM_139327.2 NP_647543.2 high mobility group protein HMG-I/HMG-Y
Protein Preferred Names Protein Names

high mobility group protein HMG-I/HMG-Y

HMG-I(Y)

high mobility group AT-hook protein 1

high mobility group protein A1

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06230 HMGA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17912 Hmga1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24381 Hmga1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HMGA1 NCBI NCBI:3159