2. Gene
  3. UBR5 - Ubr5 ubiquitin protein ligase E3 component n-recognin 5 Gene

UBR5 - Ubr5 ubiquitin protein ligase E3 component n-recognin 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Dd5; Rat100

Gene ID: 117060 | Gene type: protein coding

About UBR5

Summary

Enables protein domain specific binding activity and ubiquitin protein Ligase activity. Involved in protein ubiquitination. Located in cytosol. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human UBR5 (ubiquitin protein Ligase E3 component n-recognin 5). [provided by Alliance of Genome Resources, Apr 2022]

UBR5 Products(5)

mRNA Protein Name
XM_039080165.1 XP_038936093.1 E3 ubiquitin-protein ligase UBR5 isoform X3
XM_039080166.1 XP_038936094.1 E3 ubiquitin-protein ligase UBR5 isoform X4
XM_039080164.1 XP_038936092.1 E3 ubiquitin-protein ligase UBR5 isoform X2
XM_039080163.1 XP_038936091.1 E3 ubiquitin-protein ligase UBR5 isoform X1
XM_017595225.2 XP_017450714.1 E3 ubiquitin-protein ligase UBR5 isoform X5
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein domain specific binding IDA
IDA: Inferred from direct assay
16554297 RGD
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
12239083 RGD
enables ubiquitin protein ligase activity IMP
IMP: Inferred from mutant phenotype
7708685 RGD
Biological Process GO Annotation Evidence Reference Source
involved in protein ubiquitination IDA
IDA: Inferred from direct assay
12239083 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase UBR5

E3 ubiquitin-protein ligase UBR5-like

E3 ubiquitin-protein ligase, HECT domain-containing 1

HECT-type E3 ubiquitin transferase UBR5

hyperplastic discs protein homolog

progestin-induced protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15390 UBR5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18504 Ubr5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24986 Ubr5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens UBR5 NCBI NCBI:51366