2. Gene
  3. DNASE1L3 - Dnase1l3 deoxyribonuclease 1-like 3 Gene

DNASE1L3 - Dnase1l3 deoxyribonuclease 1-like 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 116687 | Gene type: protein coding

About DNASE1L3

Summary

Enables DNA binding activity and endodeoxyribonuclease activity. Predicted to be involved in several processes, including apoptotic DNA fragmentation; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Located in nucleus. Orthologous to human DNASE1L3 (deoxyribonuclease 1 like 3). [provided by Alliance of Genome Resources, Apr 2022]

DNASE1L3 Products(1)

mRNA Protein Name
NM_053907.1 NP_446359.1 deoxyribonuclease gamma precursor
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
9665719 RGD
enables DNA endonuclease activity IDA
IDA: Inferred from direct assay
9665719 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deoxyribonuclease gamma

DNase I-like 3

DNase gamma

DNaseY

deoxyribonuclease I-like 3

deoxyribonuclease gamma-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03897 DNASE1L3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18729 Dnase1l3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25216 Dnase1l3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens DNASE1L3 NCBI NCBI:1776
Mus musculus DNASE1L3 NCBI NCBI:13421