2. Gene
  3. Serpini1 - serpin family I member 1 Gene

Serpini1 - serpin family I member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PI-12; raPIT5a

Gene ID: 116459 | Gene type: protein coding

About Serpini1

Summary

Enables serine-type endopeptidase inhibitor activity. Involved in positive regulation of neuron projection development and regulation of cell adhesion. Predicted to be located in neuronal cell body and secretory granule lumen. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINI1 (Serpin family I member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpini1 Products(1)

mRNA Protein Name
NM_053779.2 NP_446231.1 neuroserpin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables serine-type endopeptidase inhibitor activity IDA
IDA: Inferred from direct assay
12438159 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
23825416 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuroserpin

peptidase inhibitor 12

protease inhibitor 17

serine (or cysteine) peptidase inhibitor, clade I, member 1

serine (or cysteine) proteinase inhibitor clade member 1

serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1

serine protea

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12729 SERPINI1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17787 Serpini1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24254 Serpini1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpini1 NCBI NCBI:5274
Mus musculus Serpini1 NCBI NCBI:20713