2. Gene
  3. Six1 - SIX homeobox 1 Gene

Six1 - SIX homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 114634 | Gene type: protein coding

About Six1

Summary

Enables transcription coactivator binding activity. Involved in cellular response to 3,3',5-triiodo-L-thyronine. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Orthologous to human SIX1 (SIX homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Six1 Products(1)

mRNA Protein Name
NM_053759.1 NP_446211.1 homeobox protein SIX1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables transcription coactivator binding IPI
IPI: Inferred from physical interaction
22197309 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to 3,3',5-triiodo-L-thyronine IDA
IDA: Inferred from direct assay
22197309 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein SIX1

sine oculis homeobox homolog 1

sine oculis-related homeobox 1 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-138657 NCGC00378430 Inhibitor 99.58% Unkown
HY-RS12958 SIX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17696 Six1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24158 Six1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Six1 NCBI NCBI:6495