2. Gene
  3. Hcn2 - hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 Gene

Hcn2 - hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 114244 | Gene type: protein coding

About Hcn2

Summary

Enables PDZ domain binding activity and molecular adaptor activity. Involved in several processes, including aging; cellular response to aldosterone; and response to cisplatin. Located in several cellular components, including axon; dendrite; and neuronal cell body. Biomarker of dermatitis; meningitis; and visual epilepsy. Human ortholog(s) of this gene implicated in familial febrile seizures 2. Orthologous to human HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and Sodium Channel 2). [provided by Alliance of Genome Resources, Apr 2022]

Hcn2 Products(1)

mRNA Protein Name
NM_053684.2 NP_446136.1 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Protein Preferred Names Protein Names

potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

hyperpolarization activated cyclic nucleotide-gated potassium channel 2

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-18940 Cilobradine / Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13422 Zatebradine hydrochloride Antagonist 99.87% Unkown
HY-13422A Zatebradine Antagonist 99.27% Unkown
HY-160505 RO-275 Inhibitor ≥99.0% Unkown
HY-RS06047 HCN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18617 Hcn2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25103 Hcn2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hcn2 NCBI NCBI:610