2. Gene
  3. Aipl1 - aryl hydrocarbon receptor-interacting protein-like 1 Gene

Aipl1 - aryl hydrocarbon receptor-interacting protein-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A930007I01Rik

Gene ID: 114230 | Gene type: protein coding

About Aipl1

Summary

Predicted to enable farnesylated protein binding activity. Acts upstream of or within several processes, including phototransduction, visible light; regulation of rhodopsin mediated signaling pathway; and retina homeostasis. Located in photoreceptor inner segment. Used to study Leber congenital amaurosis 4. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Leber congenital amaurosis 4; blindness; and retinitis pigmentosa. Orthologous to human AIPL1 (Aryl Hydrocarbon Receptor interacting protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Aipl1 Products(1)

mRNA Protein Name
NM_053245.2 NP_444475.2 aryl-hydrocarbon-interacting protein-like 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of apoptotic process IMP
IMP: Inferred from mutant phenotype
15365178 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15365178 MGI
acts upstream of or within phototransduction, visible light IMP
IMP: Inferred from mutant phenotype
15365173 MGI
acts upstream of or within regulation of opsin-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
15365173 MGI
acts upstream of or within retina homeostasis IMP
IMP: Inferred from mutant phenotype
15365173 MGI
Cellular Component GO Annotation Evidence Reference Source
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
14555765 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aryl-hydrocarbon-interacting protein-like 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00500 AIPL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22382 Aipl1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aipl1 NCBI NCBI:23746