2. Gene
  3. Nr2f2 - nuclear receptor subfamily 2, group F, member 2 Gene

Nr2f2 - nuclear receptor subfamily 2, group F, member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Tfcoup2

Gene ID: 113984 | Gene type: protein coding

About Nr2f2

Summary

Enables sequence-specific DNA binding activity. Involved in positive regulation of systemic arterial blood pressure; regulation of transcription, DNA-templated; and response to estradiol. Located in nucleus. Used to study hypertension. Human ortholog(s) of this gene implicated in 46,XX sex reversal 5. Orthologous to human NR2F2 (nuclear receptor subfamily 2 group F member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr2f2 Products(1)

mRNA Protein Name
NM_080778.2 NP_542956.1 COUP transcription factor 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
25687237 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12777384 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
25687237 RGD
involved in regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
12777384 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
17109907 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

COUP transcription factor 2

ARP-1

COUP transcription factor II

COUP-TF II

COUP-TF2

COUPb

apolipoprotein A-I regulatory protein 1

apolipoprotein AI regulatory protein 1

ovalbumin upstream promoter beta nuclear receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-156190A NR2F2-IN-1 free base Inhibitor 99.34% Unkown
HY-156190 NR2F2-IN-1 Inhibitor / Unkown
HY-RS09542 NR2F2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20069 Nr2f2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26573 Nr2f2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr2f2 NCBI NCBI:7026