Abcg1 - ATP binding cassette subfamily G member 1 Gene

Mus musculus

Also known as Abc8; White

Gene ID: 11307 | Gene type: protein coding

About Abcg1

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The human protein is involved in macrophage Cholesterol efflux and may regulate cellular lipid homeostasis in Other cell types. [provided by RefSeq, Jul 2008]

Abcg1 Products(1)

mRNA	Protein	Name
NM_009593.2	NP_033723.1	ATP-binding cassette sub-family G member 1

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to high density lipoprotein particle stimulus	IDA IDA: Inferred from direct assay	15210959	MGI
involved in cholesterol efflux	IMP IMP: Inferred from mutant phenotype	16556852	MGI
acts upstream of or within cholesterol transport	IDA IDA: Inferred from direct assay	15319426	MGI
involved in high-density lipoprotein particle remodeling	IMP IMP: Inferred from mutant phenotype	16556852	MGI
involved in low-density lipoprotein particle remodeling	IMP IMP: Inferred from mutant phenotype	16556852	MGI
involved in negative regulation of lipid storage	IMP IMP: Inferred from mutant phenotype	16556852	MGI
involved in positive regulation of cholesterol biosynthetic process	IMP IMP: Inferred from mutant phenotype	17916878	MGI
involved in positive regulation of cholesterol efflux	IDA IDA: Inferred from direct assay	15210959	MGI
involved in regulation of cholesterol metabolic process	IMP IMP: Inferred from mutant phenotype	16556852	MGI
involved in reverse cholesterol transport	IMP IMP: Inferred from mutant phenotype	17657311	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in endosome	IDA IDA: Inferred from direct assay	17916878	MGI
located in external side of plasma membrane	IDA IDA: Inferred from direct assay	16556852	MGI
located in recycling endosome	IDA IDA: Inferred from direct assay	16556852	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ATP-binding cassette sub-family G member 1

ATP-binding cassette 8	ATP-binding cassette transporter 8
ATP-binding cassette, sub-family G (WHITE), member 1	white protein homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-18282	AZ876	Agonist	99.77%	Unkown
HY-123148	IMB-808	Agonist	99.85%	Unkown
HY-RS00076	ABCG1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-121671	TBTC	Activator	/	Unkown
HY-RS17499	Abcg1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23956	Abcg1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Abcg1	NCBI	NCBI:9619

Name
Email *

	Sorry, but the email address you supplied was invalid.