2. Gene
  3. Pmch - pro-melanin-concentrating hormone Gene

Pmch - pro-melanin-concentrating hormone Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as A230109K23Rik

Gene ID: 110312 | Gene type: protein coding

About Pmch

Summary

This gene encodes a preproprotein that is cleaved to produce three mature peptides: melanin concentrating hormone, neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). The proprotein is processed differently depending on the tissue where it is expressed. Melanin concentrating hormone is involved in the regulation of food intake, energy homeostasis, and sleep-wake behavior. Disruption of this gene is associated with resistance to diet-induced obesity. [provided by RefSeq, May 2013]

Pmch Products(1)

mRNA Protein Name
NM_029971.2 NP_084247.1 pro-MCH preproprotein
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in feeding behavior IMP
IMP: Inferred from mutant phenotype
11867747 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nucleus IDA
IDA: Inferred from direct assay
8724342 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pro-MCH

neuropeptide-glutamic acid-isoleucine (NEI)

neuropeptide-glycine-glutamic acid (NGE)

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10759 PMCH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22282 Pmch Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28805 Pmch Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmch NCBI NCBI:5367