2. Gene
  3. Clps - colipase, pancreatic Gene

Clps - colipase, pancreatic Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2200003J09Rik

Gene ID: 109791 | Gene type: protein coding

About Clps

Summary

This gene encodes a member of the colipase family of coenzymes that is required for the optimal activity of pancreatic Lipase. The encoded protein undergoes proteolytic processing to generate a mature polypeptide that binds to the Lipase and prevents inhibition by bile acids. Over half of the mice lacking the encoded protein die within two weeks of birth while the remaining ones exhibit fat malabsorption and altered body weight regulation. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Nov 2015]

Clps Products(2)

mRNA Protein Name
NM_001317065.1 NP_001303994.1 colipase isoform 2 precursor
NM_025469.3 NP_079745.1 colipase isoform 1 preproprotein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

colipase

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P1698 Reltecimod 99.88% Phase 3
HY-P1698B Reltecimod TFA 99.78% Phase 3
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103023 CLP290 Activator 99.87% Unkown
HY-110143 CLP257 Activator 99.31% Unkown
HY-N1388 Tussilagone 99.46% Unkown
HY-12716A BRL-44408 maleate Antagonist ≥99.0% Unkown
HY-141487 CLP-3094 Inhibitor 99.92% Unkown
HY-119102 BPU-11 98.01% Unkown
HY-163409 CGK012 Inhibitor 99.96% Unkown
HY-149426 SIRT5 inhibitor 7 Inhibitor / Unkown
HY-169059 Ferroptosis-IN-12 Inhibitor / Unkown
HY-RS02829 CLP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02832 CLPS Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18608 Clps Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19585 Clp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25094 Clps Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26082 Clp1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clps NCBI NCBI:1208
Rattus norvegicus Clps NCBI NCBI:25680