UQCR11 - ubiquinol-cytochrome c reductase, complex III subunit XI Gene

Homo sapiens

Also known as UQCR; QCR10; 0710008D09Rik

Gene ID: 10975 | Gene type: protein coding

About UQCR11

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,597,169-1,605,462 (from NCBI)

This gene has 5 transcripts (splice variants) and 155 orthologues. Ubiquitous expression in colon (RPKM 36.3), fat (RPKM 35.6) and 25 other tissues.

Summary

This gene encodes the smallest known component of the ubiquinol-cytochrome c reductase complex, which forms part of the mitochondrial respiratory chain. The encoded protein may function as a binding factor for the iron-sulfur protein in this complex. [provided by RefSeq, Oct 2009]

UQCR11 Products(1)

mRNA	Protein	Name
NM_006830.4	NP_006821.1	cytochrome b-c1 complex subunit 10

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrial inner membrane	IDA IDA: Inferred from direct assay	28844695	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UQCR11 Protein Structure

UCR_6-4kD

0
56 a.a.

Protein Preferred Names

Protein Names

cytochrome b-c1 complex subunit 10

complex III subunit 10

Related Diseases

Diseases

Alias

Gracile Syndrome

Finnish Lethal Neonatal Metabolic Syndrome	Growth Retardation, Amino Aciduria, Cholestasis, Iron Overload, Lactic Acidosis, And Early Death
Flnms	Fellman Syndrome
Fellman Disease	Finnish Lactic Acidosis With Hepatic Hemosiderosis
Growth Restriction-Aminoaciduria-Cholestasis-Iron Overload-Lactic Acidosis-Early Death Syndrome	Growth Delay-Aminoaciduria-Cholestasis-Iron Overload-Lactic Acidosis-Early Death Syndrome
Lactic Acidosis, Finnish, With Hepatic Hemosiderosis	Growth Retardation, Aminoaciduria, Cholestasis, Iron Overload, Lactic Acidosis And Early Death
GRACILE

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15497	UQCR11 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20615	Uqcr11 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27123	Uqcr11 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	UQCR11	MGD	MGI:1913844
Rattus norvegicus	UQCR11	RGD	RGD:1590985

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