2. Gene
  3. U2af1 - U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 Gene

U2af1 - U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 2010107D16Rik

Gene ID: 108121 | Gene type: protein coding

About U2af1

Summary

Enables RS domain binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in nuclear speck. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and skeleton. Orthologous to human U2AF1 (U2 small nuclear RNA auxiliary factor 1). [provided by Alliance of Genome Resources, Apr 2022]

U2af1 Products(3)

mRNA Protein Name
NM_001163769.1 NP_001157241.1 splicing factor U2AF 35 kDa subunit isoform 2
NM_001357907.1 NP_001344836.1 splicing factor U2AF 35 kDa subunit isoform 3
NM_024187.4 NP_077149.2 splicing factor U2AF 35 kDa subunit isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RS domain binding IPI
IPI: Inferred from physical interaction
15798186 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18758164 MGI
Cellular Component GO Annotation Evidence Reference Source
located in nuclear speck IDA
IDA: Inferred from direct assay
18758164 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing factor U2AF 35 kDa subunit

U2 auxiliary factor 35 kDa subunit

U2 snRNP auxiliary factor small subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153736 NSC 194308 98.40% Unkown
HY-RS15313 U2AF1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18687 U2af1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25173 U2af1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens U2af1 NCBI NCBI:7307