2. Gene
  3. Chrnb3 - cholinergic receptor, nicotinic, beta polypeptide 3 Gene

Chrnb3 - cholinergic receptor, nicotinic, beta polypeptide 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Acrb3; 5730417K16Rik

Gene ID: 108043 | Gene type: protein coding

About Chrnb3

Summary

Predicted to enable acetylcholine binding activity and neurotransmitter receptor activity. Predicted to contribute to acetylcholine receptor activity. Involved in regulation of synaptic vesicle exocytosis. Located in dopaminergic synapse. Is expressed in intestine; liver; nervous system; and retina. Orthologous to human CHRNB3 (cholinergic receptor nicotinic beta 3 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrnb3 Products(2)

mRNA Protein Name
NM_027454.4 NP_081730.1 neuronal acetylcholine receptor subunit beta-3 isoform 2 precursor
NM_173212.4 NP_775304.1 neuronal acetylcholine receptor subunit beta-3 isoform 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in presynaptic modulation of chemical synaptic transmission EXP
EXP: Inferred from Experiment
14657161 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
14657161 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
14657161 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in dopaminergic synapse EXP
EXP: Inferred from Experiment
14657161 MGI
is active in dopaminergic synapse IDA
IDA: Inferred from direct assay
14657161 MGI
is active in dopaminergic synapse IMP
IMP: Inferred from mutant phenotype
14657161 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal acetylcholine receptor subunit beta-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02676 CHRNB3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21105 Chrnb3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27624 Chrnb3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrnb3 NCBI NCBI:1142