2. Gene
  3. Gldc - glycine decarboxylase Gene

Gldc - glycine decarboxylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as D19Wsu57e; b2b2679Clo; D030049L12Rik

Gene ID: 104174 | Gene type: protein coding

About Gldc

Summary

Predicted to enable anion binding activity; glycine dehydrogenase (decarboxylating) activity; and protein homodimerization activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in mitochondrion. Is expressed in several structures, including integumental system; limb; nervous system; sensory organ; and urinary system. Used to study glycine encephalopathy. Human ortholog(s) of this gene implicated in glycine encephalopathy. Orthologous to human GLDC (glycine decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Gldc Products(1)

mRNA Protein Name
NM_138595.2 NP_613061.1 glycine dehydrogenase (decarboxylating), mitochondrial precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycine dehydrogenase (decarboxylating), mitochondrial

glycine cleavage system P protein

glycine dehydrogenase (aminomethyl-transferring)

glycine dehydrogenase [decarboxylating], mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05468 GLDC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20278 Gldc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26786 Gldc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gldc NCBI NCBI:2731