Adcy3 - adenylate cyclase 3 Gene

Mus musculus

Also known as AC3; ACIII; mKIAA0511

Gene ID: 104111 | Gene type: protein coding

About Adcy3

Summary

Enables Adenylate Cyclase activity. Involved in several processes, including cAMP biosynthetic process; cellular response to forskolin; and olfactory learning. Acts upstream of or within sensory perception of smell. Located in ciliary membrane. Is integral component of membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Orthologous to human ADCY3 (Adenylate Cyclase 3). [provided by Alliance of Genome Resources, Apr 2022]

Adcy3 Products(3)

mRNA	Protein	Name
NM_001159536.1	NP_001153008.1	adenylate cyclase type 3 isoform 2
NM_001159537.1	NP_001153009.1	adenylate cyclase type 3 isoform 2
NM_138305.3	NP_612178.2	adenylate cyclase type 3 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables adenylate cyclase activity	IMP IMP: Inferred from mutant phenotype	11055432	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	12122055	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in acrosome reaction	IMP IMP: Inferred from mutant phenotype	15705663	MGI
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	11055432	MGI
involved in cAMP biosynthetic process	IMP IMP: Inferred from mutant phenotype	11055432	MGI
involved in cellular response to forskolin	IMP IMP: Inferred from mutant phenotype	11055432	MGI
involved in flagellated sperm motility	IMP IMP: Inferred from mutant phenotype	15705663	MGI
involved in olfactory learning	IMP IMP: Inferred from mutant phenotype	11055432	MGI
acts upstream of or within sensory perception of smell	IDA IDA: Inferred from direct assay	23077041	MGI
involved in sensory perception of smell	IMP IMP: Inferred from mutant phenotype	11055432	MGI
involved in single fertilization	IMP IMP: Inferred from mutant phenotype	15705663	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in ciliary membrane	IDA IDA: Inferred from direct assay	28053034	MGI
located in cilium	IDA IDA: Inferred from direct assay	11055432	MGI
located in membrane	IDA IDA: Inferred from direct assay	11055432	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

adenylate cyclase type 3

AC-III	ATP pyrophosphate-lyase 3
adenylate cyclase type III	adenylate cyclase, olfactive type
adenylyl cyclase 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00329	ADCY3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS00334	ADCY8 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS20851	Adcy3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS27365	Adcy3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Adcy3	NCBI	NCBI:109

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