2. Gene
  3. Cyp27a1 - cytochrome P450, family 27, subfamily a, polypeptide 1 Gene

Cyp27a1 - cytochrome P450, family 27, subfamily a, polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cyp27; 1300013A03Rik

Gene ID: 104086 | Gene type: protein coding

About Cyp27a1

Summary

Predicted to enable HSP70 protein binding activity; heme binding activity; and monooxygenase activity. Predicted to be involved in bile acid biosynthetic process; calcitriol biosynthetic process from calciol; and Cholesterol catabolic process. Predicted to act upstream of or within steroid biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including central nervous system; liver; male reproductive gland or organ; metanephros; and retina. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (Cytochrome P450 family 27 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp27a1 Products(1)

mRNA Protein Name
NM_024264.5 NP_077226.2 sterol 26-hydroxylase, mitochondrial precursor
Protein Preferred Names Protein Names

sterol 26-hydroxylase, mitochondrial

5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase

5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase

cholesterol 27 hydroxylase

cytochrome P-450C27/25

cytochrome P450, 27a1

sterol 27-hydroxylase

vitamin D(3) 25-hydroxylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-130705A Tachysterol 3 99.68% Unkown
HY-16670 Dafadine-A Inhibitor 98.94% Unkown
HY-138115 7ß,27-Dihydroxycholesterol Activator ≥99.0% Unkown
HY-139067 25(S)-27-Hydroxy cholesterol Activator / Unkown
HY-176497 GW273297X Inhibitor / Unkown
HY-RS03450 CYP27A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03451 CYP27B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03452 CYP27C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16287 Cyp27b1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS17011 Cyp27a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23454 Cyp27a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25766 Cyp27b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp27a1 NCBI NCBI:1593