Usp30 - ubiquitin specific peptidase 30 Gene

Mus musculus

Also known as D5Ertd483e; 6330590F17Rik

Gene ID: 100756 | Gene type: protein coding

About Usp30

Summary

Enables thiol-dependent Deubiquitinase. Involved in mitochondrial fusion and protein deubiquitination. Located in mitochondrion. Orthologous to human USP30 (ubiquitin specific peptidase 30). [provided by Alliance of Genome Resources, Apr 2022]

Usp30 Products(1)

mRNA	Protein	Name
NM_001033202.3	NP_001028374.1	ubiquitin carboxyl-terminal hydrolase 30

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables cysteine-type deubiquitinase activity	IMP IMP: Inferred from mutant phenotype	24513856	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	24513856	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in mitochondrial fusion	IMP IMP: Inferred from mutant phenotype	24513856	MGI
involved in protein deubiquitination	IMP IMP: Inferred from mutant phenotype	24513856	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrion	IDA IDA: Inferred from direct assay	24513856	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ubiquitin carboxyl-terminal hydrolase 30

deubiquitinating enzyme 30	ub-specific protease 30
ubiquitin specific protease 30	ubiquitin thioesterase 30
ubiquitin thiolesterase 30	ubiquitin-specific-processing protease 30

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-141659	CMPD-39	Inhibitor	99.74%	Unkown
HY-P10416	Q14	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Usp30	NCBI	NCBI:84749

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