2. Gene
  3. PIK3CA - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Gene

PIK3CA - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100621789 | Gene type: protein coding

About PIK3CA

Primary_assembly 13: 117,180,544-117,274,587 forward strand.Sscrofa11.1:CM000824.5

This gene has 1 transcript (splice variant), 275 orthologues and 9 paralogues. Ubiquitous expression in spleen (RPKM 7.2), lung (RPKM 6.6) and 8 other tissues.

PIK3CA Products(4)

mRNA Protein Name
XM_021069858.1 XP_020925517.1 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
XM_021069859.1 XP_020925518.1 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
XM_021069859.1 XP_020925518.1 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
XM_021069858.1 XP_020925517.1 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

PIK3CA Protein Structure

PI3K_p85B

PI3K_p85B: pfam02192 (31 - 106)

PI3K_rbd

PI3K_rbd: smart00144 (172 - 291)

C2_PI3K_class_I_alpha

C2_PI3K_class_I_alpha: cd08398 (324 - 483)

PI3Ka_I

PI3Ka_I: cd00872 (524 - 695)

PI3Kc_IA_alpha

PI3Kc_IA_alpha: cd05175 (694 - 1063)

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  • 1068 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15244 Alpelisib Inhibitor 99.95% Yes
Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-13898 Taselisib Inhibitor 99.75% Phase 3
HY-10358 MK-2206 dihydrochloride 99.99% Phase 2
HY-108232 MK-2206 / Phase 2
HY-100886 BAY1082439 98.02% Phase 1
HY-137458 Vevorisertib Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-137458A Vevorisertib trihydrochloride Inhibitor 99.13% Unkown
HY-126077 MTI-31 Inhibitor 99.98% Unkown
HY-10357 MK-2206 free base / Unkown
HY-N12726 Halociline Inhibitor / Unkown
HY-RS10523 PIK3CA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10524 Pik3ca Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10525 Pik3ca Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-116191 WJD008 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PIK3CA NCBI NCBI:5290