2. Gene
  3. ITK - IL2 inducible T cell kinase Gene

ITK - IL2 inducible T cell kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100523474 | Gene type: protein coding

About ITK

Primary_assembly 16: 66,010,772-66,082,185 reverse strand.Sscrofa11.1:CM000827.5

This gene has 2 transcripts (splice variants), 206 orthologues and 32 paralogues. Biased expression in spleen (RPKM 1.5), lung (RPKM 3.5) and 3 other tissues.

ITK Products(1)

mRNA Protein Name
XM_021076697.1 XP_020932356.1 tyrosine-protein kinase ITK/TSK

ITK Protein Structure

PH_Btk

PH_Btk: cd01238 (6 - 147)

SH3_ITK

SH3_ITK: cd11908 (173 - 228)

SH2_Tec_Itk

SH2_Tec_Itk: cd10396 (231 - 339)

PTKc_Itk

PTKc_Itk: cd05112 (357 - 612)

  • 0
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  • 500
  • 620 a.a.
Protein Preferred Names Protein Names

tyrosine-protein kinase ITK/TSK

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-109078 Vecabrutinib Inhibitor 99.76% Phase 2
Pre-clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-11092 BMS-509744 Inhibitor 98.09% Unkown
HY-12680 PRN694 Inhibitor 99.36% Unkown
HY-108691 PF-06465469 Inhibitor 99.48% Unkown
HY-150298 Soquelitinib Inhibitor 99.71% Unkown
HY-128726 ITK inhibitor 2 Inhibitor 99.66% Unkown
HY-150023 BI-1622 Inhibitor 98.97% Unkown
HY-12410 GNE-9822 Inhibitor ≥95.0% Unkown
HY-146672 ITK inhibitor 6 Inhibitor / Unkown
HY-16984 GNE-4997 Inhibitor / Unkown
HY-146671 ITK inhibitor 5 Inhibitor / Unkown
HY-149917 ITK degrader 1 Degrader / Unkown
HY-141864 ITK/TRKA-IN-1 Inhibitor / Unkown
HY-120559 GSK-2250665A Inhibitor / Unkown
HY-153322 ITK degrader 2 Degrader / Unkown
HY-143901 EGFR-IN-40 Inhibitor / Unkown
HY-13232 ITK antagonist Inhibitor / Unkown
HY-101321A Immepip dihydrobromide Degrader 99.89% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ITK NCBI NCBI:3702
Mus musculus ITK NCBI NCBI:16428