2. Gene
  3. NTRK2 - neurotrophic receptor tyrosine kinase 2 Gene

NTRK2 - neurotrophic receptor tyrosine kinase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa

Also known as TRKB

Gene ID: 100519209 | Gene type: protein coding

About NTRK2

Primary_assembly 10: 30,033,405-30,429,882 reverse strand.Sscrofa11.1:CM000821.5

This gene has 4 transcripts (splice variants), 288 orthologues and 52 paralogues. Broad expression in subcutaneous adipose (RPKM 8.6), mixtures (RPKM 6.) and 7 other tissues.

NTRK2 Products(18)

mRNA Protein Name
XM_021064648.1 XP_020920307.1 BDNF/NT-3 growth factors receptor isoform X4
XM_021064643.1 XP_020920302.1 BDNF/NT-3 growth factors receptor isoform X1
XM_021064642.1 XP_020920301.1 BDNF/NT-3 growth factors receptor isoform X1
XM_021064646.1 XP_020920305.1 BDNF/NT-3 growth factors receptor isoform X2
XM_021064644.1 XP_020920303.1 BDNF/NT-3 growth factors receptor isoform X1
XM_021064650.1 XP_020920309.1 BDNF/NT-3 growth factors receptor isoform X6
XM_021064647.1 XP_020920306.1 BDNF/NT-3 growth factors receptor isoform X3
XM_021064645.1 XP_020920304.1 BDNF/NT-3 growth factors receptor isoform X2
XM_021064649.1 XP_020920308.1 BDNF/NT-3 growth factors receptor isoform X5
XM_021064645.1 XP_020920304.1 BDNF/NT-3 growth factors receptor isoform X2
XM_021064646.1 XP_020920305.1 BDNF/NT-3 growth factors receptor isoform X2
XM_021064643.1 XP_020920302.1 BDNF/NT-3 growth factors receptor isoform X1
XM_021064642.1 XP_020920301.1 BDNF/NT-3 growth factors receptor isoform X1
XM_021064644.1 XP_020920303.1 BDNF/NT-3 growth factors receptor isoform X1
XM_021064647.1 XP_020920306.1 BDNF/NT-3 growth factors receptor isoform X3
XM_021064648.1 XP_020920307.1 BDNF/NT-3 growth factors receptor isoform X4
XM_021064649.1 XP_020920308.1 BDNF/NT-3 growth factors receptor isoform X5
XM_021064650.1 XP_020920309.1 BDNF/NT-3 growth factors receptor isoform X6

NTRK2 Protein Structure

LRR_8

LRR_8: pfam13855 (91 - 149)

TPKR_C2

TPKR_C2: pfam16920 (150 - 194)

Ig

Ig: cl11960 (204 - 282)

Ig

Ig: cd00096 (213 - 217)

Ig

Ig: cd00096 (226 - 229)

Ig

Ig: cd00096 (247 - 251)

Ig

Ig: cd00096 (261 - 267)

Ig

Ig: cd00096 (275 - 278)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (285 - 378)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (285 - 293)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (294 - 297)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (300 - 308)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (311 - 318)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (321 - 324)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (329 - 334)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (340 - 348)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (356 - 364)

IgI_TrkB_d5

IgI_TrkB_d5: cd05855 (367 - 375)

PTKc_TrkB

PTKc_TrkB: cd05093 (547 - 834)

  • 0
  • 200
  • 400
  • 600
  • 838 a.a.
Protein Preferred Names Protein Names

BDNF/NT-3 growth factors receptor

neurotrophic tyrosine kinase, receptor, type 2

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-131003 Taletrectinib Inhibitor 99.78% Phase 2
HY-131003A Taletrectinib free base Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09631 NTRK2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09632 Ntrk2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS09633 Ntrk2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NTRK2 NCBI NCBI:4915
Canis familiaris NTRK2 NCBI NCBI:484147
Mus musculus NTRK2 NCBI NCBI:18212
Rattus norvegicus NTRK2 NCBI NCBI:25054