2. Gene
  3. Msh6 - mutS homolog 6 Gene

Msh6 - mutS homolog 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 100360342 | Gene type: protein coding

About Msh6

Summary

Predicted to enable several functions, including DNA binding activity; chromatin binding activity; and methylated histone binding activity. Predicted to contribute to several functions, including DNA binding activity; MutLalpha complex binding activity; and adenyl ribonucleotide binding activity. Involved in mismatch repair and spermatogenesis. Predicted to be located in several cellular components, including Golgi apparatus; chromatin; and nucleoplasm. Predicted to be part of MutSalpha complex. Used to study hereditary nonpolyposis colorectal Cancer type 5. Human ortholog(s) of this gene implicated in Lynch syndrome; colorectal carcinoma; endometrial cancer; hereditary nonpolyposis colorectal Cancer type 5; and mismatch repair Cancer syndrome. Orthologous to human MSH6 (mutS homolog 6). [provided by Alliance of Genome Resources, Apr 2022]

Msh6 Products(1)

mRNA Protein Name
NM_001398548.1 NP_001385477.1 mutS homolog 6
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in mismatch repair IMP
IMP: Inferred from mutant phenotype
18417481 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
10644444 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA mismatch repair protein Msh6

mutS homolog 6

rCG61559-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08713 MSH6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22241 Msh6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28763 Msh6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Msh6 NCBI NCBI:2956