ZNF717 - zinc finger protein 717 Gene

Homo sapiens

Also known as OB1; X17; ZNF838

Gene ID: 100131827 | Gene type: protein coding

About ZNF717

Cytogenetic location: 3p12.3 Genomic coordinates (GRCh38): 3:75,694,701-75,785,549 (from NCBI)

This gene has 7 transcripts (splice variants), 20 orthologues and 174 paralogues. Ubiquitous expression in testis (RPKM 1.7), thyroid (RPKM 1.6) and 25 other tissues.

Summary

This gene encodes a Kruppel-associated box (KRAB) zinc-finger protein, which belongs to a large group of transcriptional regulators in mammals. These proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation and Apoptosis, and in regulating viral replication and transcription. A pseudogene of this gene was identified on chromosome 1. [provided by RefSeq, May 2016]

ZNF717 Products(7)

mRNA	Protein	Name
NM_001128223.3	NP_001121695.1	zinc finger protein 717 isoform a
NM_001290208.3	NP_001277137.1	zinc finger protein 717 isoform a
NM_001290209.3	NP_001277138.1	zinc finger protein 717 isoform b
NM_001290210.2	NP_001277139.1	zinc finger protein 717 isoform c
NM_001324026.2	NP_001310955.1	zinc finger protein 717 isoform c
NM_001324027.1	NP_001310956.1	zinc finger protein 717 isoform d
NM_001324028.1	NP_001310957.1	zinc finger protein 717 isoform e

ZNF717 Protein Structure

KRAB

zf-H2C2_2

0
200
400
600
800
907 a.a.

Protein Preferred Names

Protein Names

zinc finger protein 717

krueppel-like factor X17

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16170	ZNF717 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ZNF717	RGD	RGD:1306633
Mus musculus	ZNF717	MGD	MGI:99183

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