CCR5 - C-C motif chemokine receptor 5 Gene

Oryctolagus cuniculus

Also known as CCR-5; CMKBR5; CC-CKR-5

Gene ID: 100101579 | Gene type: protein coding

About CCR5

Chromosome 9: 14,558,940-14,562,221 forward strand.OryCun2.0:CM000798.1

This gene has 1 transcript (splice variant), 150 orthologues and 21 paralogues.

mRNA	Protein	Name
NM_001171125.1	NP_001164596.1	C-C chemokine receptor type 5

7tmA_CCR5_CCR2

Protein Preferred Names

Protein Names

C-C chemokine receptor type 5

C-C CKR-5	C-C chemokine receptor 5
CC chemokine receptor 5	MIP-1 alpha receptor

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13004	Maraviroc	Antagonist	99.88%	Yes
HY-117621	PF-04634817	Antagonist	98.87%	Unkown
HY-117621A	PF-04634817 succinate	Antagonist	≥99.0%	Unkown

Clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Phase
HY-14882	Cenicriviroc	Antagonist	99.01%	Phase 3
HY-14882A	Cenicriviroc Mesylate	Antagonist	99.04%	Phase 3
HY-17377	Vicriviroc maleate	Antagonist	99.91%	Phase 3
HY-17450A	Aplaviroc hydrochloride	Antagonist	99.76%	Phase 3
HY-17450	Aplaviroc	Antagonist	/	Phase 3
HY-109593	BMS-813160	Antagonist	99.93%	Phase 2
HY-P1034	DAPTA	Inhibitor	99.85%	Phase 2
HY-14230	INCB9471	Antagonist	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (11)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13406	TAK-779	Antagonist	99.73%	Unkown
HY-101713	Ilacirnon	Inhibitor	99.87%	Unkown
HY-19974	TAK-220	Antagonist	99.95%	Unkown
HY-119101	AZD-5672	Antagonist	95.74%	Unkown
HY-111069	Nifeviroc	Inhibitor	98.17%	Unkown
HY-111321	Fuscin	Inhibitor	/	Unkown
HY-162512	CB-0821	Inhibitor	/	Unkown
HY-108432	BMS-741672	Antagonist	/	Unkown
HY-152132	CCR5 antagonist 3	Inhibitor	/	Unkown
HY-100261	CCR5 antagonist 1	Antagonist	/	Unkown
HY-152131	CCR5 antagonist 2	Antagonist	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	CCR5	NCBI	NCBI:1234
Mus musculus	CCR5	NCBI	NCBI:12774

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