1. Apoptosis
  2. Ferroptosis
  3. FSP1-IN-1

FSP1-IN-1 (compound 39) is a potent FSP1 inhibitor with an IC50 of 35 nM. FSP1-IN-1 enhances RSL3 (HY-100218A)-induced lipid peroxide accumulation and sensitizes cancer cells to ferroptosis.

For research use only. We do not sell to patients.

FSP1-IN-1 Chemical Structure

FSP1-IN-1 Chemical Structure

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Description

FSP1-IN-1 (compound 39) is a potent FSP1 inhibitor with an IC50 of 35 nM. FSP1-IN-1 enhances RSL3 (HY-100218A)-induced lipid peroxide accumulation and sensitizes cancer cells to ferroptosis[1].

Molecular Weight

464.54

Formula

C23H24N6O3S

SMILES

COC1=CC=C(C2=NN=C3N2N=C(CN4CCN(C5=CC=C(C(OC)=O)C=C5)CC4)S3)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FSP1-IN-1
Cat. No.:
HY-172896
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