2. GPCR/G Protein Anti-infection
  3. Formyl Peptide Receptor (FPR) Bacterial
  4. fMIFL

fMIFL is an FPR1 agonist. fMIFL can activate several signaling pathways responsible for various neutrophil functions, such as adhesion, chemotaxis, secretion of granule exocytosis, and the production of superoxide anions. fMIFL can be used in research on bacterial infections and tissue damage.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

fMIFL

fMIFL Chemical Structure

CAS No. : 112275-26-0

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Based on 1 publication(s) in Google Scholar

fMIFL Related Antibodies

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Description

fMIFL is an FPR1 agonist. fMIFL can activate several signaling pathways responsible for various neutrophil functions, such as adhesion, chemotaxis, secretion of granule exocytosis, and the production of superoxide anions. fMIFL can be used in research on bacterial infections and tissue damage[1].
Molecular Weight

550.71

Formula

C27H42N4O6S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{N-formyl}-Met-Ile-Phe-Leu
Sequence Shortening

{N-formyl}-MIFL
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

H2O : 7.1 mg/mL (12.89 mM; ultrasonic and warming and adjust pH to 8 with NH4OH)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8158 mL 9.0792 mL 18.1584 mL
5 mM 0.3632 mL 1.8158 mL 3.6317 mL
View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.8158 mL 9.0792 mL 18.1584 mL 45.3959 mL
5 mM 0.3632 mL 1.8158 mL 3.6317 mL 9.0792 mL
10 mM 0.1816 mL 0.9079 mL 1.8158 mL 4.5396 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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fMIFL Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

fMIFL112275-26-0Formyl Peptide Receptor (FPR)Bacterialneutrophil functionadhesionchemotaxisgranule exocytosisInhibitorinhibitorinhibit

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