Fluorescein hydrazide

Cat. No.: HY-151644 Purity: 98.90%: Data Sheet
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Fluorescein hydrazide is a sensitive fluorescent probe for Hg²⁺ and Co²⁺ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM[2][3].

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Fluorescein hydrazide Chemical Structure

CAS No. : 78044-20-9

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Based on 1 publication(s) in Google Scholar

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Description	Fluorescein hydrazide is a sensitive fluorescent probe for Hg²⁺ and Co²⁺ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM^[1][2][3].
In Vitro	Fluorescein hydrazide forms a complex with Hg²⁺, which in turn triggers structural changes in the Fluorescein hydrazide molecule, causes changes in its absorption and fluorescence spectra, thereby resulting the color and fluorescence intensity of Fluorescein hydrazide solution^[2]. Fluorescein hydrazide can be used for detection of mercury pollution in water, food and biological samples, which can be applied in environmental monitoring, food safety and biomedicine^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Fluorescein hydrazide Related Antibodies
Molecular Weight	346.34
Formula	C₂₀H₁₄N₂O₄
CAS No.	78044-20-9
Appearance	Solid
Color	White to off-white
Emission (Em)	523
Excitation (Ex)	488
SMILES	O=C1C=CC2=C(C3=C(C(NN)=O)C=CC=C3)C4=C(C=C(C=C4)O)OC2=C1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation	Purity: 98.90% Select Batch: Data Sheet (272 KB) SDS (252 KB) COA (253 KB) HNMR (143 KB) RP-HPLC (168 KB) LCMS (379 KB) Handling Instructions (2659 KB)
References	[1]. Yusha Feng, et al. A novel "turn-on" thiooxofluorescein-based colorimetric and fluorescent sensor for Hg2+ and its application in living cells. Talanta. 2017 Aug 1;170:103-110. [Content Brief] [2]. Xie Z, et al. Sensitive colorimetric and fluorescent detection of mercury using fluorescein derivations[J]. 2012. [3]. Mori I, et al., Selective and sensitive fluorometric determinations of cobalt(II) and hydrogen peroxide with fluorescein-hydrazide. Talanta. 1998 Nov;47(3):631-7. [Content Brief]