2. Immunology/Inflammation
  3. FAP
  4. FAP-IN-2 TFA

FAP-IN-2 TFA is a 99mTc-labeled isonitrile-containing FAP inhibitor derivative that can be used for tumor imaging.

For research use only. We do not sell to patients.

FAP-IN-2 TFA

FAP-IN-2 TFA Chemical Structure

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5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of FAP-IN-2 TFA:

FAP-IN-2 TFA Related Antibodies

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Description

FAP-IN-2 TFA is a 99mTc-labeled isonitrile-containing FAP inhibitor derivative that can be used for tumor imaging[1].

Molecular Weight

828.58

Formula

C30H31F11N6O9
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCN4CCNCC4)C=C3)=O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (301.72 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 100 mg/mL (120.69 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2069 mL 6.0344 mL 12.0688 mL
5 mM 0.2414 mL 1.2069 mL 2.4138 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.2069 mL 6.0344 mL 12.0688 mL 30.1721 mL
5 mM 0.2414 mL 1.2069 mL 2.4138 mL 6.0344 mL
10 mM 0.1207 mL 0.6034 mL 1.2069 mL 3.0172 mL
15 mM 0.0805 mL 0.4023 mL 0.8046 mL 2.0115 mL
20 mM 0.0603 mL 0.3017 mL 0.6034 mL 1.5086 mL
25 mM 0.0483 mL 0.2414 mL 0.4828 mL 1.2069 mL
30 mM 0.0402 mL 0.2011 mL 0.4023 mL 1.0057 mL
40 mM 0.0302 mL 0.1509 mL 0.3017 mL 0.7543 mL
50 mM 0.0241 mL 0.1207 mL 0.2414 mL 0.6034 mL
60 mM 0.0201 mL 0.1006 mL 0.2011 mL 0.5029 mL
80 mM 0.0151 mL 0.0754 mL 0.1509 mL 0.3772 mL
100 mM 0.0121 mL 0.0603 mL 0.1207 mL 0.3017 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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FAP-IN-2 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAP-IN-2FAPFibroblast activation proteinInhibitorinhibitorinhibit

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