2. Membrane Transporter/Ion Channel
  3. Sodium Channel Potassium Channel
  4. Eleclazine hydrochloride (Standard)

Eleclazine hydrochloride (Standard) 

Cat. No.: HY-16738AR Purity: ≥98%
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Eleclazine (hydrochloride) (Standard) is the analytical standard of Eleclazine (hydrochloride). This product is intended for research and analytical applications. Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 μM and approximately 14.2 μM, respectively. Eleclazine hydrochloride shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine hydrochloride can be used to research cardiac arrhythmias.

For research use only. We do not sell to patients.

Eleclazine hydrochloride (Standard) Chemical Structure

Eleclazine hydrochloride (Standard) Chemical Structure

CAS No. : 1448754-43-5

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Description

Eleclazine (hydrochloride) (Standard) is the analytical standard of Eleclazine (hydrochloride). This product is intended for research and analytical applications. Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 μM and approximately 14.2 μM, respectively. Eleclazine hydrochloride shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine hydrochloride can be used to research cardiac arrhythmias.

Molecular Weight

451.83

Formula

C21H17ClF3N3O3
CAS No.
SMILES

O=C1N(CC2=NC=CC=N2)CCOC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=C13.[H]Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Eleclazine hydrochloride (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Eleclazine hydrochloride (Standard)1448754-43-5Sodium ChannelPotassium ChannelNa channelsNa+ channelsKcsAatrial premature beatsporcinecardiac arrhythmiashiPSCepinephrineInhibitorinhibitorinhibit

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