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  4. EDTA-OH

EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils. EDTA-OH is able to cross brain-blood barrier.

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EDTA-OH

EDTA-OH Chemical Structure

CAS No. : 150-39-0

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Based on 1 publication(s) in Google Scholar

EDTA-OH Related Antibodies

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Description

EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper[1]. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils[2]. EDTA-OH is able to cross brain-blood barrier[3].

In Vivo

EDTA-OH (50 mg/kg, i.p. for 5 days) decreases the aluminium concentration in blood and brain and oxidative stress in brain. EDTA-OH is blood-brain barrier permeable, which could be an antidote for aluminium overload[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Aluminium overload in wistar rats[3]
Dosage: 50 mg/kg
Administration: i.p. for 5 days
Result: Inhibited GST activity, reduced the concentration of aluminium in blood and brain.
Molecular Weight

278.26

Formula

C10H18N2O7
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CN(CCO)CCN(CC(O)=O)CC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 17.5 mg/mL (62.89 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5938 mL 17.9688 mL 35.9376 mL
5 mM 0.7188 mL 3.5938 mL 7.1875 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 97.11%

SDS (614 KB)

COA (247 KB) HNMR (124 KB) LCMS (237 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.5938 mL 17.9688 mL 35.9376 mL 89.8440 mL
5 mM 0.7188 mL 3.5938 mL 7.1875 mL 17.9688 mL
10 mM 0.3594 mL 1.7969 mL 3.5938 mL 8.9844 mL
15 mM 0.2396 mL 1.1979 mL 2.3958 mL 5.9896 mL
20 mM 0.1797 mL 0.8984 mL 1.7969 mL 4.4922 mL
25 mM 0.1438 mL 0.7188 mL 1.4375 mL 3.5938 mL
30 mM 0.1198 mL 0.5990 mL 1.1979 mL 2.9948 mL
40 mM 0.0898 mL 0.4492 mL 0.8984 mL 2.2461 mL
50 mM 0.0719 mL 0.3594 mL 0.7188 mL 1.7969 mL
60 mM 0.0599 mL 0.2995 mL 0.5990 mL 1.4974 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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EDTA-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EDTA-OH150-39-0Biochemical Assay Reagentsbrain-blood barrierphytoremediationwistar ratInhibitorinhibitorinhibit

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