Echinosporin  (Synonyms: XK-213)

Echinosporin (XK-213) is an antibiotic. Echinosporin can be isolated from Amycolatopsis strain. Echinosporin has antifungal activity and antitumor activity^[1][2].

MIC50: 64 μg/mL (Fusarium oxysporum); 64 μg/mL (Fusarium solani); 32 μg/mL (Alternaria panax); 64 μg/mL (Phoma herbarum)^[2].

Echinosporin (XK-213) exhibits weak antibacterial activities against Gram-positive and -negative microorganisms and its shows antitumor activity^[1].
Echinosporin exhibits antifungal activity against root-rot pathogens of Panax notoginseng include Fusarium oxysporum, Fusarium solani, Alternaria panax, and Phoma herbarum with the MIC₅₀ value at 64, 64, 32, and 64 μg/mL, respectively^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

223.18

C₁₀H₉NO₅

79127-35-8

O=C(C1=C[C@@]([C@@](C(O2)=O)(O)C=C3)([H])[C@@]3([H])[C@@]2([H])O1)N

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. T Sato, et al. A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterization. J Antibiot (Tokyo). 1982 Mar;35(3):266-71.  [Content Brief]

  [2]. Xindong Xu, et al. Echinosporin antibiotics isolated from Amycolatopsis strain and their antifungal activity against root-rot pathogens of the Panax notoginseng. Folia Microbiol (Praha). 2019 Mar;64(2):171-175.  [Content Brief]