2. Metabolic Enzyme/Protease GPCR/G Protein
  3. Lipoxygenase Prostaglandin Receptor
  4. E 3040

E 3040 is an orally active dual inhibitor of 5-lipoxygenase and thromboxane synthase. E 3040 exhibits anti-inflammatory effect.

For research use only. We do not sell to patients.

E 3040

E 3040 Chemical Structure

CAS No. : 145096-30-6

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E 3040 Related Antibodies

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Description

E 3040 is an orally active dual inhibitor of 5-lipoxygenase and thromboxane synthase. E 3040 exhibits anti-inflammatory effect[1].

IC50 & Target[1]

5-Lipoxygenase

 

In Vivo

E 3040 (30-100 mg/kg, p.o.) shows anti-inflammation effect in LPS (HY-D1056)-treated rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: LPS (HY-D1056)-treated rats[1]
Dosage: 30 and 100 mg/kg
Administration: Orally administration
Result: Inhibited the increase in vascular permeability.
Inhibited the production of leukotriene B(4) and thromboxane B(2).
Increased the production of prostaglandin E(2).
Molecular Weight

299.39

Formula

C16H17N3OS
CAS No.
SMILES

OC1=C(C)C(CC2=CC=CN=C2)=C3N=C(NC)SC3=C1C
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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E 3040 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E 3040145096-30-6E3040E-3040LipoxygenaseProstaglandin ReceptorLOX5-lipoxygenasethromboxane synthaseLPSanti-inflammatoryInhibitorinhibitorinhibit

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