2. Apoptosis
  3. Bcl-2 Family
  4. Dimebutic acid sodium

Dimebutic acid sodium  (Synonyms: NSC-16045 sodium; NSC-741804 sodium)

Cat. No.: HY-W015881A
Handling Instructions Technical Support

Dimebutic acid sodium is an orally active short-chain fatty acid. Dimebutic acid sodium stimulates fetal globin production and alters the balance of Bcl family proteins. Dimebutic acid sodium prolongs red blood cell survival. Dimebutic acid sodium exhibits toxicity in rats. Dimebutic acid sodium can be used in the study of β-thalassemia and sickle cell disease.

For research use only. We do not sell to patients.

Dimebutic acid sodium

Dimebutic acid sodium Chemical Structure

CAS No. : 3934-02-9

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of Dimebutic acid sodium:

Other Forms of Dimebutic acid sodium:

Dimebutic acid sodium Related Antibodies

Top Publications Citing Use of Products

View All Bcl-2 Family Isoform Specific Products:

View All Isoforms
Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim BNIP3

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Dimebutic acid sodium is an orally active short-chain fatty acid. Dimebutic acid sodium stimulates fetal globin production and alters the balance of Bcl family proteins. Dimebutic acid sodium prolongs red blood cell survival. Dimebutic acid sodium exhibits toxicity in rats. Dimebutic acid sodium can be used in the study of β-thalassemia and sickle cell disease[1][2].

In Vivo

Dimebutic acid (200-1000 mg/kg; p.o.; once daily; up to 15 days) sodium causes toxic reactions such as ataxia and weight loss at high doses (1000 mg/kg) in the Sprague-Dawley rat model[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats (male: 200-260 g, female: 160-220 g)[2]
Dosage: 200 mg/kg, 600 mg/kg, 1000 mg/kg
Administration: Oral gavage (p.o.)
Result: Did not cause mortality in any dose group.
Showed ataxia for females, had rough coat and thin appearance for males (at 1000 mg/kg).
Showed frequent functional observational battery (FOB) deficits in females, including decreased body tone, rectal temperature, etc.
Decreased RBC, HGB, HCT and increased reticulocytes at high doses.
Increased liver and kidney weights at 1000 mg/kg.
Molecular Weight

138.14

Formula

C6H11NaO2
CAS No.
SMILES

CCC(C)(C(O[Na])=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Dimebutic acid sodium Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dimebutic acid3934-02-9NSC-16045NSC-741804NSC16045NSC 16045NSC741804NSC 741804Bcl-2 FamilyInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Dimebutic acid sodium
Cat. No.:
HY-W015881A
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.