2. Metabolic Enzyme/Protease
  3. PDHK
  4. DHNA

DHNA (KIS20) is a PDH kinase 4 (PDK4) inhibitor with an IC50 of 18 μM. DHNA can be used for the study of heart failure.

For research use only. We do not sell to patients.

DHNA

DHNA Chemical Structure

CAS No. : 117255-85-3

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Based on 1 publication(s) in Google Scholar

DHNA Related Antibodies

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Description

DHNA (KIS20) is a PDH kinase 4 (PDK4) inhibitor with an IC50 of 18 μM. DHNA can be used for the study of heart failure[1].

Molecular Weight

204.18

Formula

C11H8O4
CAS No.
Appearance

Solid

Color

Off-white to gray

SMILES

O=C(C1=CC=C2C(O)=CC=C(O)C2=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (489.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8976 mL 24.4882 mL 48.9764 mL
5 mM 0.9795 mL 4.8976 mL 9.7953 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.8976 mL 24.4882 mL 48.9764 mL 122.4410 mL
5 mM 0.9795 mL 4.8976 mL 9.7953 mL 24.4882 mL
10 mM 0.4898 mL 2.4488 mL 4.8976 mL 12.2441 mL
15 mM 0.3265 mL 1.6325 mL 3.2651 mL 8.1627 mL
20 mM 0.2449 mL 1.2244 mL 2.4488 mL 6.1220 mL
25 mM 0.1959 mL 0.9795 mL 1.9591 mL 4.8976 mL
30 mM 0.1633 mL 0.8163 mL 1.6325 mL 4.0814 mL
40 mM 0.1224 mL 0.6122 mL 1.2244 mL 3.0610 mL
50 mM 0.0980 mL 0.4898 mL 0.9795 mL 2.4488 mL
60 mM 0.0816 mL 0.4081 mL 0.8163 mL 2.0407 mL
80 mM 0.0612 mL 0.3061 mL 0.6122 mL 1.5305 mL
100 mM 0.0490 mL 0.2449 mL 0.4898 mL 1.2244 mL
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DHNA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DHNA117255-85-31,4-Dihydroxy-6-naphthoic acidPDHKPyruvate dehydrogenase kinasePDH kinasePDK4heart failureInhibitorinhibitorinhibit

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