2. Anti-infection
  3. HCV
  4. Deleobuvir

Deleobuvir (BI 207127) is a potent non-nucleoside hepatitis C virus (HCV) NS5B polymerase inhibitor.

For research use only. We do not sell to patients.

The Deleobuvir was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

Deleobuvir Chemical Structure

Deleobuvir Chemical Structure

CAS No. : 863884-77-9

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Deleobuvir:

Deleobuvir Related Antibodies

Top Publications Citing Use of Products

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Description

Deleobuvir (BI 207127) is a potent non-nucleoside hepatitis C virus (HCV) NS5B polymerase inhibitor.

Clinical Trial
Molecular Weight

653.57

Formula

C34H33BrN6O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN1C(C2=NC=C(Br)C=N2)=C(C3CCCC3)C4=CC=C(C(NC5(C(N(C6=C7)C)=NC6=CC=C7/C=C/C(O)=O)CCC5)=O)C=C41
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 6.6 mg/mL (10.10 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5301 mL 7.6503 mL 15.3006 mL
5 mM 0.3060 mL 1.5301 mL 3.0601 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5301 mL 7.6503 mL 15.3006 mL 38.2514 mL
5 mM 0.3060 mL 1.5301 mL 3.0601 mL 7.6503 mL
10 mM 0.1530 mL 0.7650 mL 1.5301 mL 3.8251 mL
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Deleobuvir Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deleobuvir863884-77-9BI 207127BI207127BI-207127HCVHepatitis C virusInhibitorinhibitorinhibit

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