1. Natural Products
  2. Plants Flavonoids
  3. Leguminosae Other Flavonoids
  4. Amorpha fruticosaL.
  5. Dehydrodeguelin

Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L.

For research use only. We do not sell to patients.

Dehydrodeguelin

Dehydrodeguelin Chemical Structure

CAS No. : 3466-23-7

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Based on 1 publication(s) in Google Scholar

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Description

Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L[1].

Cellular Effect
Cell Line Type Value Description References
Astrocyte IC50
> 80 μM
Compound: 2
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
Growth inhibition of Nf1 defective and Trp53 defective mouse primary astrocytes after 2 hrs by XTT assay
[PMID: 26467198]
B16 IC50
0.56 μM
Compound: 8
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse B16 cells assessed as reduction in cell viability by MTT assay
[PMID: 28665590]
HepG2 IC50
0.56 μM
Compound: 8
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
[PMID: 28665590]
L5178Y IC50
10.2 μM
Compound: 28
Cytotoxicity against mouse L5178Y cells by MTT assay
Cytotoxicity against mouse L5178Y cells by MTT assay
[PMID: 28075580]
Lewis lung carcinoma cell line IC50
0.56 μM
Compound: 8
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse LL/2 cells assessed as reduction in cell viability by MTT assay
[PMID: 28665590]
NCI-H1299 IC50
> 500 μM
Compound: 12
Cytotoxicity against human H1299 cells after 3 days by MTS assay
Cytotoxicity against human H1299 cells after 3 days by MTS assay
[PMID: 23186287]
Molecular Weight

392.40

Formula

C23H20O6

CAS No.
SMILES

O=C1C2=C(COC3=CC(OC)=C(OC)C=C32)OC4=C5C=CC(C)(C)OC5=CC=C14

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Dehydrodeguelin
Cat. No.:
HY-N3712
Quantity:
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