2. Anti-infection
  3. HIV
  4. Decanoyl-RVKR-CMK TFA

Decanoyl-RVKR-CMK TFA  (Synonyms: DecRVKRcmk TFA)

Cat. No.: HY-107760A Purity: 95.63%
COA
SDS
Handling Instructions Technical Support

Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Decanoyl-RVKR-CMK TFA

Decanoyl-RVKR-CMK TFA Chemical Structure

CAS No. : 2098497-25-5

Size Price Stock Quantity
1 mg In-stock
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Decanoyl-RVKR-CMK TFA:

Decanoyl-RVKR-CMK TFA Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Decanoyl-RVKR-CMK TFA

View All HIV Isoform Specific Products:

View All Isoforms
HIV HIV-1 HIV-2

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication[1].

IC50 & Target

HIV-1

 

HIV-2

 

In Vitro

Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits HIV-2ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell[1].
? Decanoyl-RVKR-CMK (DecRVKRcmk) TFA blocks regulated secretion of VGF[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Decanoyl-RVKR-CMK TFA Related Antibodies

Cell Viability Assay[1]

Cell Line: HeLaCD4 cells infected with recombinant vaccinia viruses at a multiplicity of infection (MOI) of 5 PFU/mL
Concentration: 35 and 70 µΜ
Incubation Time: 7 days
Result: Peptide at 35 µM significantly inhibited ex vivo HIV-1 and HIV-2 replications (70-80% inhibition).
Molecular Weight

858.43

Formula

C36H67ClF3N11O7
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (116.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 4 mg/mL (4.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1649 mL 5.8246 mL 11.6492 mL
5 mM 0.2330 mL 1.1649 mL 2.3298 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.04%

SDS (252 KB)

COA (247 KB) RP-HPLC (111 KB) MS (224 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.1649 mL 5.8246 mL 11.6492 mL 29.1229 mL
DMSO 5 mM 0.2330 mL 1.1649 mL 2.3298 mL 5.8246 mL
10 mM 0.1165 mL 0.5825 mL 1.1649 mL 2.9123 mL
15 mM 0.0777 mL 0.3883 mL 0.7766 mL 1.9415 mL
20 mM 0.0582 mL 0.2912 mL 0.5825 mL 1.4561 mL
25 mM 0.0466 mL 0.2330 mL 0.4660 mL 1.1649 mL
30 mM 0.0388 mL 0.1942 mL 0.3883 mL 0.9708 mL
40 mM 0.0291 mL 0.1456 mL 0.2912 mL 0.7281 mL
50 mM 0.0233 mL 0.1165 mL 0.2330 mL 0.5825 mL
60 mM 0.0194 mL 0.0971 mL 0.1942 mL 0.4854 mL
80 mM 0.0146 mL 0.0728 mL 0.1456 mL 0.3640 mL
100 mM 0.0116 mL 0.0582 mL 0.1165 mL 0.2912 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Decanoyl-RVKR-CMK TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Decanoyl-RVKR-CMK2098497-25-5DecRVKRcmkHIVHuman immunodeficiency virusglycoproteinVGF glycoproteinVGFHIV-2 ROD infectionreplicationInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Decanoyl-RVKR-CMK TFA
Cat. No.:
HY-107760A
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB) Italian - IT (252 KB) Portuguese - PT (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.