2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  3. Microtubule/Tubulin Apoptosis
  4. cis-3,4',5-Trimethoxy-3'-hydroxystilbene

cis-3,4',5-Trimethoxy-3'-hydroxystilbene 

Cat. No.: HY-118452 Purity: 99.59%
COA
SDS
Handling Instructions Technical Support

cis-3,4',5-Trimethoxy-3'-hydroxystilbene is a stilbene. cis-3,4',5-Trimethoxy-3'-hydroxystilbene induces cytochrome c release to the cytoplasm. cis-3,4',5-Trimethoxy-3'-hydroxystilbene-induced apoptosis is associated with mitochondrial release of cytochrome c. cis-3,4',5-Trimethoxy-3'-hydroxystilbene also suppresses tubulin polymerization. cis-3,4',5-Trimethoxy-3'-hydroxystilbene can be used for leukemic research.

For research use only. We do not sell to patients.

cis-3,4',5-Trimethoxy-3'-hydroxystilbene Chemical Structure

cis-3,4',5-Trimethoxy-3'-hydroxystilbene Chemical Structure

CAS No. : 586410-08-4

Size Price Stock Quantity
1 mg In-stock
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

cis-3,4',5-Trimethoxy-3'-hydroxystilbene Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

cis-3,4',5-Trimethoxy-3'-hydroxystilbene is a stilbene. cis-3,4',5-Trimethoxy-3'-hydroxystilbene induces cytochrome c release to the cytoplasm. cis-3,4',5-Trimethoxy-3'-hydroxystilbene-induced apoptosis is associated with mitochondrial release of cytochrome c. cis-3,4',5-Trimethoxy-3'-hydroxystilbene also suppresses tubulin polymerization. cis-3,4',5-Trimethoxy-3'-hydroxystilbene can be used for leukemic research[1].

Cellular Effect
Cell Line Type Value Description References
HL-60 IC50
30 nM
Compound: 1b
Induction of apoptosis in human HL60 cells by flow cytometry
Induction of apoptosis in human HL60 cells by flow cytometry
[PMID: 19117761]
SNU-423 IC50
15 nM
Compound: 1b
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
Cytotoxicity against human SNU423 cells after 48 hrs by alamar blue assay
[PMID: 19117761]
In Vitro

cis-3,4',5-Trimethoxy-3'-hydroxystilbene (10-500 nM) eliminates the colony-forming ability of HL60 cells[1].
cis-3,4',5-Trimethoxy-3'-hydroxystilbene (10-500 nM) induces dose-dependent apoptosis in HL60 cells but does not affect bone marrow progenitor cells[1].
cis-3,4',5-Trimethoxy-3'-hydroxystilbene (0-100 μM) inhibits tubulin polymerization in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

cis-3,4',5-Trimethoxy-3'-hydroxystilbene Related Antibodies
Molecular Weight

286.32

Formula

C17H18O4
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

OC(C=C1/C=C\C2=CC(OC)=CC(OC)=C2)=C(C=C1)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

cis-3,4',5-Trimethoxy-3'-hydroxystilbene Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cis-3,4',5-Trimethoxy-3'-hydroxystilbene586410-08-4Microtubule/TubulinApoptosisHL60 cellsbone marrow progenitor cellstubulin polymerizationleukemicInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
cis-3,4',5-Trimethoxy-3'-hydroxystilbene
Cat. No.:
HY-118452
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (393 KB) Français - FR (393 KB) Deutsch - DE (393 KB) Norwegian - NO (393 KB) Español - ES (393 KB) Swedish - SV (393 KB) Italian - IT (393 KB) Portuguese - PT (393 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.