2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK2-IN-30

CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 value ≤20 nM. CDK2-IN-30 can be used in tumor research.

For research use only. We do not sell to patients.

CDK2-IN-30 Chemical Structure

CDK2-IN-30 Chemical Structure

CAS No. : 2640038-22-6

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Based on 1 publication(s) in Google Scholar

CDK2-IN-30 Related Antibodies

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Description

CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 value ≤20 nM. CDK2-IN-30 can be used in tumor research[1].

IC50 & Target

CDK2

≤ 20 nM (IC50)

Molecular Weight

419.50

Formula

C18H25N7O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCOC1=C(C2=CNN=C2)C=CN3C1=NC(N[C@@H]4[C@@H](CN(CC4)S(C)(=O)=O)C)=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (238.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3838 mL 11.9190 mL 23.8379 mL
5 mM 0.4768 mL 2.3838 mL 4.7676 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3838 mL 11.9190 mL 23.8379 mL 59.5948 mL
5 mM 0.4768 mL 2.3838 mL 4.7676 mL 11.9190 mL
10 mM 0.2384 mL 1.1919 mL 2.3838 mL 5.9595 mL
15 mM 0.1589 mL 0.7946 mL 1.5892 mL 3.9730 mL
20 mM 0.1192 mL 0.5959 mL 1.1919 mL 2.9797 mL
25 mM 0.0954 mL 0.4768 mL 0.9535 mL 2.3838 mL
30 mM 0.0795 mL 0.3973 mL 0.7946 mL 1.9865 mL
40 mM 0.0596 mL 0.2980 mL 0.5959 mL 1.4899 mL
50 mM 0.0477 mL 0.2384 mL 0.4768 mL 1.1919 mL
60 mM 0.0397 mL 0.1986 mL 0.3973 mL 0.9932 mL
80 mM 0.0298 mL 0.1490 mL 0.2980 mL 0.7449 mL
100 mM 0.0238 mL 0.1192 mL 0.2384 mL 0.5959 mL
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CDK2-IN-30 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK2-IN-302640038-22-6CDKCyclin dependent kinaseInhibitorant-itumorinhibitorinhibit

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