2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Calcium Channel antagonist 6

Calcium Channel antagonist 6 (Compound 328) is a highly selective antagonist of voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. Calcium Channel antagonist 6 inhibits of neuron depolarization-induced Ca2+ influx. Calcium Channel antagonist 6 is promising for research of neuropathic pain.

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Calcium Channel antagonist 6 Chemical Structure

Calcium Channel antagonist 6 Chemical Structure

CAS No. : 687568-35-0

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Calcium Channel antagonist 6 Related Antibodies

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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Description

Calcium Channel antagonist 6 (Compound 328) is a highly selective antagonist of voltage-gated calcium channel CaV2.2 with an IC50 value of 0.37 μM. Calcium Channel antagonist 6 inhibits of neuron depolarization-induced Ca2+ influx. Calcium Channel antagonist 6 is promising for research of neuropathic pain[1].

IC50 & Target

CaV2.2

 

Molecular Weight

451.54

Formula

C21H29N3O6S
CAS No.
SMILES

O=C(N1CCN(CC1)C(C2=C(C)C3=C(C=CC(S(=O)(N(CC)CC)=O)=C3)O2)=O)OCC
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Calcium Channel antagonist 6 Related Classifications

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Keywords:

Calcium Channel antagonist 6687568-35-0Calcium Channel antagonist6Calcium Channel antagonist-6Calcium ChannelCa2+ channelsCa channelsvoltage-gated calcium channel CaV2.2neuron depolarizationneuropathic painInhibitorinhibitorinhibit

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