Butyrophenone (Synonyms: 1-Phenylbutan-1-one; 1-Phenyl-1-butanone)

Cat. No.: HY-W010265 Purity: 98.96%: Data Sheet
COA

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Handling Instructions
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Butyrophenone (1-Phenylbutan-1-one) is a dopamine receptor (DA Receptor) antagonist and can be used in research on mental disorders.

For research use only. We do not sell to patients.

Butyrophenone Chemical Structure

CAS No. : 495-40-9

Size	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Liquid
10 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Other Forms of Butyrophenone:

Butyrophenone-d₅ Get quote
Butyrophenone (Standard) Get quote

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Biological Activity
Purity & Documentation
References
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Description

Butyrophenone (1-Phenylbutan-1-one) is a dopamine receptor (DA Receptor) antagonist and can be used in research on mental disorders^[1]^[2].

Molecular Weight

148.20

Formula

C₁₀H₁₂O

CAS No.

495-40-9

Appearance

Liquid

Color

Colorless to light yellow

SMILES

CCCC(C1=CC=CC=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : ≥ 175 mg/mL (1180.84 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.7476 mL	33.7382 mL	67.4764 mL
5 mM	1.3495 mL	6.7476 mL	13.4953 mL
10 mM	0.6748 mL	3.3738 mL	6.7476 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.96%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (246 KB) HNMR (242 KB) GC (242 KB)

Handling Instructions (2659 KB)

References

[1]. Waddington J L, et al. Functional Heterogeneity of Multiple Dopamine Receptors during Six Months' Treatment with Distinct Classes of Neuroleptic Drugs[M]//Advances in Dopamine Research. Pergamon, 1982: 143-146.

[2]. Chilakapati J et al. Butyrophenones[J]. 2014.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.7476 mL	33.7382 mL	67.4764 mL	168.6910 mL
	5 mM	1.3495 mL	6.7476 mL	13.4953 mL	33.7382 mL
	10 mM	0.6748 mL	3.3738 mL	6.7476 mL	16.8691 mL
	15 mM	0.4498 mL	2.2492 mL	4.4984 mL	11.2461 mL
	20 mM	0.3374 mL	1.6869 mL	3.3738 mL	8.4345 mL
	25 mM	0.2699 mL	1.3495 mL	2.6991 mL	6.7476 mL
	30 mM	0.2249 mL	1.1246 mL	2.2492 mL	5.6230 mL
	40 mM	0.1687 mL	0.8435 mL	1.6869 mL	4.2173 mL
	50 mM	0.1350 mL	0.6748 mL	1.3495 mL	3.3738 mL
	60 mM	0.1125 mL	0.5623 mL	1.1246 mL	2.8115 mL
	80 mM	0.0843 mL	0.4217 mL	0.8435 mL	2.1086 mL
	100 mM	0.0675 mL	0.3374 mL	0.6748 mL	1.6869 mL

Butyrophenone Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Butyrophenone495-40-91-Phenylbutan-1-one 1-Phenyl-1-butanoneDopamine ReceptorMental disordersInhibitorinhibitorinhibit

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