2. Immunology/Inflammation
  3. AP-1
  4. BRP

BRP, a BRINP2-related peptide, possesses anti-obesity activity via FOS activation. BRP central FOS activation and acts independently of leptin, GLP-1 receptor and melanocortin 4 receptor.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

BRP

BRP Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of BRP:

BRP Related Antibodies

Top Publications Citing Use of Products

View All AP-1 Isoform Specific Products:

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c-Fos FosB Fra1/FOSL1 Fra2/FOSL2 c-Jun

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Description

BRP, a BRINP2-related peptide, possesses anti-obesity activity via FOS activation. BRP central FOS activation and acts independently of leptin, GLP-1 receptor and melanocortin 4 receptor[1].

Molecular Weight

1540.88

Formula

C68H117N25O14S
Appearance

Solid

Sequence

Thr-His-Arg-Ile-Leu-Arg-Arg-Leu-Phe-Asn-Leu-Cys-NH2
Sequence Shortening

THRILRRLFNLC-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (64.90 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6490 mL 3.2449 mL 6.4898 mL
5 mM 0.1298 mL 0.6490 mL 1.2980 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.6490 mL 3.2449 mL 6.4898 mL 16.2245 mL
5 mM 0.1298 mL 0.6490 mL 1.2980 mL 3.2449 mL
10 mM 0.0649 mL 0.3245 mL 0.6490 mL 1.6224 mL
15 mM 0.0433 mL 0.2163 mL 0.4327 mL 1.0816 mL
20 mM 0.0324 mL 0.1622 mL 0.3245 mL 0.8112 mL
25 mM 0.0260 mL 0.1298 mL 0.2596 mL 0.6490 mL
30 mM 0.0216 mL 0.1082 mL 0.2163 mL 0.5408 mL
40 mM 0.0162 mL 0.0811 mL 0.1622 mL 0.4056 mL
50 mM 0.0130 mL 0.0649 mL 0.1298 mL 0.3245 mL
60 mM 0.0108 mL 0.0541 mL 0.1082 mL 0.2704 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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BRP Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BRPBRINP2-related peptideAP-1Activator Protein 1Inhibitorinhibitorinhibit

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