2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. Bromobenzene-d5

Bromobenzene-d5  (Synonyms: pentadeuterobromobenzene)

Cat. No.: HY-Z0056S Purity: 98.66%
COA
SDS
Handling Instructions Technical Support

Bromobenzene-d5 is the deuterium labeled Bromobenzene. Bromobenzene is a well-known environmental toxin which causes liver and kidney damage through CYP450-mediated bio-activation to generate reactive metabolites and, consequently, oxidative stress.

For research use only. We do not sell to patients.

Bromobenzene-d<sub>5</sub>

Bromobenzene-d5 Chemical Structure

CAS No. : 4165-57-5

Size Price Stock Quantity
1 g Get quote 2-4 weeks 2-4 weeks 2-4 weeks
5 g Get quote 2-4 weeks 2-4 weeks 2-4 weeks
10 g Get quote 2-4 weeks 2-4 weeks 2-4 weeks
25 g Get quote 2-4 weeks 2-4 weeks 2-4 weeks
50 g   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Bromobenzene-d5 Related Antibodies

Top Publications Citing Use of Products

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Bromobenzene-d5 is the deuterium labeled Bromobenzene. Bromobenzene is a well-known environmental toxin which causes liver and kidney damage through CYP450-mediated bio-activation to generate reactive metabolites and, consequently, oxidative stress[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bromobenzene-d5 Related Antibodies
Molecular Weight

162.04

Formula

C6D5Br
CAS No.
Unlabeled CAS
Appearance

Liquid (Density: 1.539 g/cm3)

Color

Colorless to light yellow

SMILES

BrC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (1234.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.1713 mL 30.8564 mL 61.7128 mL
5 mM 1.2343 mL 6.1713 mL 12.3426 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.1713 mL 30.8564 mL 61.7128 mL 154.2819 mL
5 mM 1.2343 mL 6.1713 mL 12.3426 mL 30.8564 mL
10 mM 0.6171 mL 3.0856 mL 6.1713 mL 15.4282 mL
15 mM 0.4114 mL 2.0571 mL 4.1142 mL 10.2855 mL
20 mM 0.3086 mL 1.5428 mL 3.0856 mL 7.7141 mL
25 mM 0.2469 mL 1.2343 mL 2.4685 mL 6.1713 mL
30 mM 0.2057 mL 1.0285 mL 2.0571 mL 5.1427 mL
40 mM 0.1543 mL 0.7714 mL 1.5428 mL 3.8570 mL
50 mM 0.1234 mL 0.6171 mL 1.2343 mL 3.0856 mL
60 mM 0.1029 mL 0.5143 mL 1.0285 mL 2.5714 mL
80 mM 0.0771 mL 0.3857 mL 0.7714 mL 1.9285 mL
100 mM 0.0617 mL 0.3086 mL 0.6171 mL 1.5428 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Bromobenzene-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bromobenzene-d54165-57-5pentadeuterobromobenzeneCytochrome P450CYPsdeuteriumtoxinliverkidney damagereactive metabolitesoxidative stressInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Bromobenzene-d5
Cat. No.:
HY-Z0056S
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (688 KB) Français - FR (688 KB) Deutsch - DE (688 KB) Norwegian - NO (688 KB) Español - ES (688 KB) Swedish - SV (688 KB) Italian - IT (688 KB) Portuguese - PT (688 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.