1. Epigenetics Cell Cycle/DNA Damage Autophagy Apoptosis Immunology/Inflammation
  2. Epigenetic Reader Domain FKBP
  3. BRD4/FKBP12 degrader-2

BRD4/FKBP12 degrader-2 (a1dj) is a BRD4/FKBP12 degrader and shows anticancer activity (BRD4 ligand: HY-78695, FKBP12 ligand: HY-176502, linker: HY-140212).

For research use only. We do not sell to patients.

BRD4/FKBP12 degrader-2 Chemical Structure

BRD4/FKBP12 degrader-2 Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

BRD4/FKBP12 degrader-2 (a1dj) is a BRD4/FKBP12 degrader and shows anticancer activity (BRD4 ligand: HY-78695, FKBP12 ligand: HY-176502, linker: HY-140212)[1].

Molecular Weight

1049.49

Formula

C48H52Cl3N11O6S2

SMILES

O=C(NCCOCCN1C=C(COC[C@H]2CN(C([C@@]3([H])N([C@]2([H])CCC3)S(C4=CC(Cl)=CC(Cl)=C4)(=O)=O)=O)[C@@H](C)C5=NC=CC=C5)N=N1)C[C@@H]6N=C(C7=CC=C(Cl)C=C7)C8=C(SC(C)=C8C)N9C6=NN=C9C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
BRD4/FKBP12 degrader-2
Cat. No.:
HY-176477
Quantity:
MCE Japan Authorized Agent: