1. Apoptosis Autophagy
  2. Bcl-2 Family Beclin1
  3. BRD1991

BRD1991 selectively disrupts Beclin 1/Bcl-2 binding and induces autophagy without triggering apoptosis or other forms of cell death.

For research use only. We do not sell to patients.

BRD1991

BRD1991 Chemical Structure

CAS No. : 2235468-02-5

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Description

BRD1991 selectively disrupts Beclin 1/Bcl-2 binding and induces autophagy without triggering apoptosis or other forms of cell death[1].

In Vitro

BRD1991 (20 μM, 24 h) can induce complete autophagic flux in HeLa/GFP-LC3 cells, exhibit mild cytotoxicity, and gradually accumulate intracellularly over time[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

608.55

Formula

C33H35Cl2N3O4

CAS No.
SMILES

CN1C2=CC=CC=C2C3=C1C(N(C(CO)C)CC(C)C(CN(C(C4=CC(Cl)=CC(Cl)=C4)=O)C)OCC5=CC=CC=C53)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BRD1991
Cat. No.:
HY-125191
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