2. Metabolic Enzyme/Protease
  3. Neprilysin
  4. BL-2401

BL-2401 is an orally active enkephalinase inhibitor. BL-2401 exhibit antinociceptive and antidepressant-like activitiesin association with endogenous opioid systems. BL-2401 can be used for the research of neurological disease.

For research use only. We do not sell to patients.

BL-2401

BL-2401 Chemical Structure

CAS No. : 151774-56-0

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BL-2401 Related Antibodies

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Description

BL-2401 is an orally active enkephalinase inhibitor. BL-2401 exhibit antinociceptive and antidepressant-like activitiesin association with endogenous opioid systems. BL-2401 can be used for the research of neurological disease[1].

In Vivo

BL-2401 (p.o.) produces an antinociceptive effect in the mouse phenylbenzoquinone writhing test (ED50 = 12.4 mg/kg) and the rat acetic acid writhing test (ED50 = 55.8 mg/kg)[1].
BL-2401 (100 mg/kg, p.o.) produces a naloxone-reversible antidepressant-like effect in the mouse forced swimming test[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

385.48

Formula

C21H23NO4S
CAS No.
SMILES

CCC(SCC(CC1=CC=CC=C1)C(NC2=CC(C(O)=O)=CC(C)=C2)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BL-2401 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BL-2401151774-56-0BL2401BL 2401NeprilysinNeutral endopeptidaseNEPCluster of differentiation 10CD10Enkephalinaseantinociceptiveantidepressantopioid systemsneurologicalInhibitorinhibitorinhibit

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