Bis-PEG4-NHS ester

Cat. No.: HY-130086 Purity: ≥97.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Bis- PEG4- NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).

For research use only. We do not sell to patients.

Bis-PEG4-NHS ester Chemical Structure

Size	Stock	Quantity
Free Sample (0.1 - 0.2 mg)	Apply Now
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
250 mg	In-stock	Estimated Time of Arrival: December 31
500 mg	Get quote
1 g	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All ADC Linker Isoform Specific Products:

View All Isoforms

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Biological Activity
Purity & Documentation
Customer Review

Description

Bis- PEG4- NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC).

IC₅₀ & Target

Non-cleavable Linker

Molecular Weight

488.44

Formula

C₂₀H₂₈N₂O₁₂

CAS No.

1314378-11-4

Appearance

Solid

Color

White to off-white

SMILES

O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 66.67 mg/mL (136.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0473 mL	10.2367 mL	20.4733 mL
5 mM	0.4095 mL	2.0473 mL	4.0947 mL
10 mM	0.2047 mL	1.0237 mL	2.0473 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (239 KB) SDS (393 KB)

COA (244 KB) HNMR (266 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0473 mL	10.2367 mL	20.4733 mL	51.1834 mL
	5 mM	0.4095 mL	2.0473 mL	4.0947 mL	10.2367 mL
	10 mM	0.2047 mL	1.0237 mL	2.0473 mL	5.1183 mL
	15 mM	0.1365 mL	0.6824 mL	1.3649 mL	3.4122 mL
	20 mM	0.1024 mL	0.5118 mL	1.0237 mL	2.5592 mL
	25 mM	0.0819 mL	0.4095 mL	0.8189 mL	2.0473 mL
	30 mM	0.0682 mL	0.3412 mL	0.6824 mL	1.7061 mL
	40 mM	0.0512 mL	0.2559 mL	0.5118 mL	1.2796 mL
	50 mM	0.0409 mL	0.2047 mL	0.4095 mL	1.0237 mL
	60 mM	0.0341 mL	0.1706 mL	0.3412 mL	0.8531 mL
	80 mM	0.0256 mL	0.1280 mL	0.2559 mL	0.6398 mL
	100 mM	0.0205 mL	0.1024 mL	0.2047 mL	0.5118 mL