2. Metabolic Enzyme/Protease
  3. Serpin
  4. Belcesiran

Belcesiran, a siRNA, is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.

For research use only. We do not sell to patients.

Gene Regulation Tool

RNA, (Am-sp-Am-(2'-deoxy-2'-fluoro)A-Cm-Cm-Cm-Um-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)U-Um-Cm-Um-(2'-deoxy-2'-fluoro)U-Am-Am-Am-Gm-Cm-Am-Gm-Cm-Cm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]G-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm), complex with RNA ([1-de-β-D-ribofuranosyl-1-[(2R,3R,4S,5S)-tetrahydro-4-hydroxy-5-[(hydroxymethoxyphosphinyl)methoxy]-3-methoxy-2-furanyl]]U-(4'→5')-sp-(2'-deoxy-2'-fluoro)U-sp-(2'-deoxy-2'-fluoro)U-sp-Am-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Am-Gm-Am-Cm-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Gm-Um-(2'-deoxy-2'-fluoro)U-Um-sp-Gm-sp-Gm) (1:1)

Belcesiran Chemical Structure

CAS No. : 2375562-54-0

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Belcesiran Related Antibodies

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Description

Belcesiran, a siRNA, is an alpha 1 antitrypsin (A1AT) inhibitor that acts by allowing the liver to synthesise the A1AT protein and pass it into the bloodstream.

Molecular Weight

21033.20

Formula

C666H877O417N231F15P57S6
CAS No.
SMILES

[Belcesiran]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Belcesiran Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Belcesiran2375562-54-0DCR-S1459SerpinSerine protease inhibitors (Serpins)Inhibitorinhibitorinhibit

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