1. GPCR/G Protein Neuronal Signaling
  2. Cholecystokinin Receptor
  3. BC264

BC264 is a highly potent and selective CCK-B agonist that crosses the blood-brain barrier. BC264 increases dopamine in the nucleus accumbens and facilitates motivation and attention in rats.

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BC264

BC264 Chemical Structure

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Description

BC264 is a highly potent and selective CCK-B agonist that crosses the blood-brain barrier. BC264 increases dopamine in the nucleus accumbens and facilitates motivation and attention in rats[1].

IC50 & Target [1]

CCKBR

 

In Vivo

BC264 (0.3-30 μg/kg; i.p.; once) increases the exploration of rats submitted to an unknown territory but were devoid of anxiogenic properties in the elevated plus maze. BC264 increases locomotion and rearings of rats newly placed in an open field and improved their spontaneous alternation in a Y-maze[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1221.44

Formula

C58H80N10O15S2

SMILES

NC([C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCCC)N(C)C([C@@H](NC(CNC([C@H](CCCC)NC([C@H](CCSC)NC([C@H](CC2=CC=C(S(=O)(O)=O)C=C2)NC(OC(C)(C)C)=O)=O)=O)=O)=O)CC3=CNC4=C3C=CC=C4)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
BC264
Cat. No.:
HY-177508
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